Self-controlled hyperthermia is a non-invasive technique used to kill or destroy cancer cells while preserving normal surrounding tissues. We have explored bulk magnetic Ni-Si and Ni-Al alloys as a potential thermoseeds. The structural, magnetic and magnetocaloric properties of the samples were investigated, including saturation magnetisation, Curie temperature (TC), and magnetic and thermal hysteresis, using room temperature X-ray diffraction and magnetometry. The annealing time, temperature and the effects of homogenising the thermoseeds were studied to determine the functional hyperthermia applications. The bulk Ni-Si and Ni-Al binary alloys have Curie temperatures in the desired range, 316 K–319 K (43 °C–46 °C), which is suitable for magnetic hyperthermia applications. We have found that TC strictly follows a linear trend with doping concentration over a wide range of temperature. The magnetic ordering temperature and the magnetic properties can be controlled through substitution in these binary alloys.
Publication Source (Journal or Book title)
International Journal of Hyperthermia
Pandey, S., Quetz, A., Aryal, A., Dubenko, I., Mazumdar, D., Stadler, S., & Ali, N. (2017). Magnetic, structural and magnetocaloric properties of Ni-Si and Ni-Al thermoseeds for self-controlled hyperthermia. International Journal of Hyperthermia, 33 (7), 779-784. https://doi.org/10.1080/02656736.2017.1312562