Current research in radiotracer imaging of electroporation injury
High-voltage electrical shock can produce minimal external signs of damage with widespread damage to the skeletal muscle. The injury can be thermally mediated or the result of electroporation of cell membranes. Radiotracer imaging is one method for assessing the extent of damage in skeletal muscle. We are using radiotracer imaging in an in vivo animal model to investigate the effects of novel therapies, such as surfactants, for repairing electroporation damage. In this work, we report the results of region-of-interest (ROI) analysis and principal component analysis (PCA) of the data collected from the animal model. These analytical methods may provide a tool to assist in clinical monitoring of electrical injury victims.
Publication Source (Journal or Book title)
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Matthews, K., Chen, T., Aarsvold, J., Mintzer, R., Cooper, M., Block, T., Capelli-Schellpfeffer, M., & Lee, R. (1996). Current research in radiotracer imaging of electroporation injury. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 5, 2187-2188. Retrieved from https://digitalcommons.lsu.edu/physics_astronomy_pubs/3393