Brain image analysis using spherical splines

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Conference Proceeding

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We propose a novel technique based on spherical splines for brain surface representation and analysis. This research is strongly inspired by the fact that, for brain surfaces, it is both necessary and natural to employ spheres as their natural domains. We develop an automatic and efficient algorithm, which transforms a brain surface to a single spherical spline whose maximal error deviation from the original data is less than the user-specified tolerance. Compared to the discrete mesh-based representation, our spherical spline offers a concise (low storage requirement) digital form with high continuity (C n-1 continuity for a degree n spherical spline). Furthermore, this representation enables the accurate evaluation of differential properties, such as curvature, principal direction, and geodesic, without the need for any numerical approximations. Thus, certain shape analysis procedures, such as segmentation, gyri and sulci tracing, and 3D shape matching, can be carried out both robustly and accurately. We conduct several experiments in order to demonstrate the efficacy of our approach for the quantitative measurement and analysis of brain surfaces. © Springer-Verlag Berlin Heidelberg 2005.

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Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

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