Title

Bio-magnetic bead separator on glass chips using semi-encapsulated spiral electromagnets

Document Type

Conference Proceeding

Publication Date

1-1-1997

Abstract

A new planar bio-magnetic bead separator on a glass chip has been designed, fabricated and tested. The separator is composed of micromachined semi-encapsulated spiral electromagnets and fluid channels, which are separately fabricated and then bonded. The device was tested with super-paramagnetic beads of mean diameter 0.83 μm which were suspended in a buffered solution with solid concentration 10%. When a DC current of 300 mA was applied to the inductor, the bio-magnetic beads were successfully attached on the electromagnets, showing a functional capability as a magnetic bead separator. Using this separator, cells or cell fragments and magnetic beads bonded with protein or enzyme suspended in bio-buffer solutions can be successfully separated from their suspensions.

Publication Source (Journal or Book title)

International Conference on Solid-State Sensors and Actuators, Proceedings

First Page

485

Last Page

488

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