Title

New technologies for measuring single cell mass

Document Type

Article

Publication Date

2-21-2014

Abstract

Characterizing the physical properties of single cells is of great interest for unraveling the heterogeneity in a cell population. Recent advances in micro-systems technologies and quantitative imaging have enabled measurements of the mass and growth of single cells. So far, three classes of techniques have been reported for such measurements. These are suspended micro-channel resonators (SMR) sensors, quantitative phase imaging (QPI), and pedestal resonant sensors. Here we compare the unique merits of each method and discuss their potential to evolve into multi-modal platforms for answering fundamental questions in biology and medicine. © 2014 The Royal Society of Chemistry.

Publication Source (Journal or Book title)

Lab on a Chip

First Page

646

Last Page

652

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