Title
Pulsed valve matrix-assisted ionization
Document Type
Article
Publication Date
5-21-2017
Abstract
© 2017 The Royal Society of Chemistry. We have developed a new ionization approach for matrix-assisted ionization with high temporal resolution using an electrically actuated pulsed valve. Matrix and analyte samples are deposited on a thin metal foil and placed at the inlet of an ambient ionization mass spectrometer. When the pulsed valve is actuated, a short puff of high pressure gas impinges on the foil and ejects particulate from the sample on the opposite side. Highly charged ions are formed from the particles at the mass spectrometer inlet. Using this source, multiply charged protein ions are produced within a selectable 4 second time window.
Publication Source (Journal or Book title)
Analyst
First Page
1672
Last Page
1675
Recommended Citation
Banstola, B., & Murray, K. (2017). Pulsed valve matrix-assisted ionization. Analyst, 142 (10), 1672-1675. https://doi.org/10.1039/c7an00489c