Synthesis of Cycloparaphenyleneacetylene via Alkyne Metathesis: C70 Complexation and Copper-Free Triple Click Reaction
© 2016 American Chemical Society. Alkyne metathesis provided an efficient macrocyclization route to a cycloparaphenyleneacetylene derivative in high yield. The cavity size was suitably matched for C70 which was tightly bound in an induced-fit fashion. The strained alkynes enabled a copper-free, 3-fold azide-alkyne cycloaddition at 50 °C.
Publication Source (Journal or Book title)
Journal of the American Chemical Society
Lee, S., Chénard, E., Gray, D., & Moore, J. (2016). Synthesis of Cycloparaphenyleneacetylene via Alkyne Metathesis: C70 Complexation and Copper-Free Triple Click Reaction. Journal of the American Chemical Society, 138 (42), 13814-13817. https://doi.org/10.1021/jacs.6b08752