Title

Mechanistic insights into Brønsted acid-induced nucleophilic substitution of aliphatic imidazole carbamate with halide ions

Document Type

Article

Publication Date

3-11-2015

Abstract

© 2015 Elsevier Ltd. All rights reserved. Herein we report interesting reactivity of imidazole carbamate towards nucleophilic substitution with halide ions under Brønsted acidic conditions. Depending upon reaction conditions, halide ions could readily attack the carboxyl position and trigger decarboxylative alkyl halide formation. Alternatively, halide ions were also found to competitively undergo nucleophilic acyl substitution, which ultimately results in the generation of carbonate dimerization product.

Publication Source (Journal or Book title)

Tetrahedron Letters

First Page

1392

Last Page

1396

This document is currently not available here.

Share

COinS