Title
An expedient synthesis of functionalized 1,4-diketone-derived compounds via silyloxyallyl cation intermediates
Document Type
Article
Publication Date
2-7-2016
Abstract
© The Royal Society of Chemistry 2016. Herein we describe a new method, enabling the synthesis of highly functionalized 1,4-diketones that are readily differentiated as monosilylenol ethers under Brønsted acid catalysis. This synthetically useful chemistry exploited an intermediacy of unsymmetrical silyloxyallyl cations, which were directly captured by silyl enolates to create the targeted α,α carbon-carbon linkages in a regioselective manner. Our reaction conditions proved to be mild, rendering the silylenol ether functionalities intact.
Publication Source (Journal or Book title)
Chemical Communications
First Page
2300
Last Page
2303
Recommended Citation
Stepherson, J., Fronczek, F., & Kartika, R. (2016). An expedient synthesis of functionalized 1,4-diketone-derived compounds via silyloxyallyl cation intermediates. Chemical Communications, 52 (11), 2300-2303. https://doi.org/10.1039/c5cc09763k