Title

Manipulation and capture of Aβ amyloid fibrils and monomers by DC insulator gradient dielectrophoresis (DC-iGDEP)

Document Type

Article

Publication Date

7-21-2012

Abstract

Here we report a novel method for the manipulation and concentration of Aβ amyloid fibrils, implicated in Alzheimer's disease, using DC insulating gradient dielectrophoresis (DC-iGDEP). Fibril enrichment was found to be ∼400%. Simulations suggest that capture of the full range of amyloid protein aggregates is possible with optimized device design. © 2012 The Royal Society of Chemistry.

Publication Source (Journal or Book title)

Analyst

First Page

3227

Last Page

3229

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