Title
Manipulation and capture of Aβ amyloid fibrils and monomers by DC insulator gradient dielectrophoresis (DC-iGDEP)
Document Type
Article
Publication Date
7-21-2012
Abstract
Here we report a novel method for the manipulation and concentration of Aβ amyloid fibrils, implicated in Alzheimer's disease, using DC insulating gradient dielectrophoresis (DC-iGDEP). Fibril enrichment was found to be ∼400%. Simulations suggest that capture of the full range of amyloid protein aggregates is possible with optimized device design. © 2012 The Royal Society of Chemistry.
Publication Source (Journal or Book title)
Analyst
First Page
3227
Last Page
3229
Recommended Citation
Staton, S., Jones, P., Ku, G., Gilman, S., Kheterpal, I., & Hayes, M. (2012). Manipulation and capture of Aβ amyloid fibrils and monomers by DC insulator gradient dielectrophoresis (DC-iGDEP). Analyst, 137 (14), 3227-3229. https://doi.org/10.1039/c2an35138b