Title

Selective protonation at a C-F bond in the presence of an iridium-methyl bond gives diastereoselective carbon-fluorine bond activation and carbon-carbon bond formation. A new path to carbon stereocenters bearing fluorine atoms

Document Type

Article

Publication Date

11-11-2002

Abstract

Reaction of iridium-fluoroalkyl complexes with fluoride acceptors occurred with completely diastereoselective activation of a C-F bond and formation of a new C-C bond. Protonation occurred with complete selectivity at the C-F bond without any detectable formation of methane by protonation at the Ir-CH3 group. It was also found that the protonation reaction occurred with no elimination of methane.

Publication Source (Journal or Book title)

Organometallics

First Page

4902

Last Page

4904

This document is currently not available here.

Share

COinS