Title

Novel instrument for measurement of multidimensional fluorescence detected circular dichroism

Document Type

Article

Publication Date

12-1-1986

Abstract

A new microprocessor-controlled multichannel spectrometer for the measurement of fluorescence detected circular dichroism (FDCD) is presented. Spectra of model steroid compounds are provided to demonstrate the analytical utility of multichannel FDCD over the classical circular dichroism measurement. A detection limit of 3.05×10-8 M was determined for a solution of estrone based on a signal/noise ratio of 2 as a lower limit. The optics and electronics for the rapid acquisition of multichannel FDCD data are described in detail.

Publication Source (Journal or Book title)

Review of Scientific Instruments

First Page

1308

Last Page

1313

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