The influence of mobile phase alcohol modifiers on hplc of polycyclic aromatics using bonded phase cyclodextrin columns
Recent studies have shown that formation constants for cyclodextrin inclusion complexes are increased in the presence of certain alcohols. This paper describes a preliminary investigation of the effects of mobile phase alcohol modifiers on HPLC separation of polynuclear aromatics using cyclodextrin bonded phases. Dramatic changes in the chromatography are reported in the presence of alcohol. Some discussion is provided as to how these results may be used to increase the selectivity of HPLC separations using cyclodextrin bonded phases. Copyright © 1988 by Marcel Dekker, Inc.
Publication Source (Journal or Book title)
Tarr, M., Nelson, G., Patonay, G., & Warner, I. (1988). The influence of mobile phase alcohol modifiers on hplc of polycyclic aromatics using bonded phase cyclodextrin columns. Analytical Letters, 21 (5), 843-856. https://doi.org/10.1080/00032718808070863