Influence of Alcohols on the β-Cyclodextrin/Acridine Complex
The apparent formation constant calculated for the β-cyclodextrin/acridine (β-CD/ACR) complex (287 M−1) reveals a weak association in aqueous solution. An additional weakening of the binding strength between β-CD and ACR, and subsequent reduction in the previously reported quenching of ACR caused by β-CD, is observed upon interaction of the complex with selected straight-chain and branched alcohols. Nuclear magnetic resonance data suggest that the equilibrium involves the formation of ternary complexes. This equilibrium apparently leaves a greater number of ACR species accessible to the bulk aqueous environment, resulting in a consequent decrease in the total amount of ACR quenched. Specific mechanisms of interaction are further examined through information provided by steady-state fluorescence and fluorescence lifetime analysis. © 1993, American Chemical Society. All rights reserved.
Publication Source (Journal or Book title)
Journal of the American Chemical Society
Schuette, J., Ndou, T., de la Peña, A., Mukundan, S., & Warner, I. (1993). Influence of Alcohols on the β-Cyclodextrin/Acridine Complex. Journal of the American Chemical Society, 115 (1), 292-298. https://doi.org/10.1021/ja00054a042