Title

Chiral electrokinetic chromatography using dipeptide polymeric surfactants: Present state of the art

Document Type

Article

Publication Date

1-1-1999

Abstract

Polymeric amino acid based surfactants have been recently employed as pseudostationary phases in capillary electrophoresis. These phases are effective for chiral separation of analytes in different charge states and hydrophobicities. This review paper focuses on polymeric dipeptide surfactants. The benefits of dipeptide over single amino acid micelle polymers are shown. Some aspects of dipeptide surfactants that are presented here includes the amino acid order, effect of number and position of chiral centers, and steric factors on enantiomeric separation of chiral compounds in different charge states. In addition, the preferential site of interaction of the chiral analyte using diastereomers of polymeric dipeptide surfactants is discussed.

Publication Source (Journal or Book title)

Electrophoresis

First Page

3011

Last Page

3026

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