Title

Syntheses of porphyrin and chlorin dimers for photodynamic therapy (Invited Paper)

Document Type

Conference Proceeding

Publication Date

1-1-1991

Abstract

Efficient methods for the syntheses of porphyrin and chlorin dimers joined with variable length carbon units, either at meso positions or at β-pyrrolic positions, are described. The in vivo testing results for some of the dimers are also discussed. The main objective of this work is to understand the structure/activity relationships among carbon-carbon linked dimers of porphyrins and chlorins. It is anticipated that this study will assist the authors in designing photosensitizers with required chemical and photochemical properties.

Publication Source (Journal or Book title)

Proceedings of SPIE - The International Society for Optical Engineering

First Page

356

Last Page

361

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