"Synthesis of a porphyrin-labelled carboranyl phosphate diester: A pote" by Andreas Maderna, Ramon Huertas et al.

Faculty Publications

Title

Synthesis of a porphyrin-labelled carboranyl phosphate diester: A potential new drug for boron neutron capture therapy of cancer

Authors

Andreas Maderna, University of California, Los Angeles
Ramon Huertas, University of California, Los Angeles
M. Frederick Hawthorne, University of California, Los Angeles
Raymond Luguya, Louisiana State University
M. Graça H. Vicente, Louisiana State University

Document Type

Article

Publication Date

1-1-2002

Abstract

A boron-rich, water-soluble porphyrin conjugate was synthesized by coupling of two carboranyl alcohols with 2-chlorophenoxyphosphorus dichloride, followed by conjugation to an amine-functionalized tetraphenyl-porphyrin via an amide linkage.

Publication Source (Journal or Book title)

Chemical Communications

First Page

1784

Last Page

1785

Recommended Citation

Maderna, A., Huertas, R., Hawthorne, M., Luguya, R., & Vicente, M. (2002). Synthesis of a porphyrin-labelled carboranyl phosphate diester: A potential new drug for boron neutron capture therapy of cancer. Chemical Communications, 16, 1784-1785. https://doi.org/10.1039/b203730k

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