Novel carboranylporphyrins for application in boron neutron capture therapy (BNCT) of tumors
Condensation of a new carboranylpyrrole 1 with benzaldehydes leads to β-carboranylporphyrins 2 and 3 in good yields. These new porphyrins of high boron content (32-43%) have potential as boron delivery agents for BNCT. The X-ray structures of one β-carboranylporphyrin, of a carboranylpyrrole, and of a side-product are presented. © 2005 Elsevier Ltd. All rights reserved.
Publication Source (Journal or Book title)
Clark, J., Fronczek, F., & Vicente, M. (2005). Novel carboranylporphyrins for application in boron neutron capture therapy (BNCT) of tumors. Tetrahedron Letters, 46 (14), 2365-2368. https://doi.org/10.1016/j.tetlet.2005.02.077