Syntheses and properties of octa-, tetra-, and di-hydroxy-substituted phthalocyanines
The synthesis and photophysical properties of a new series of zinc(II) phthalocyanines (ZnPcs) bearing multiple hydroxy and tert-butyl groups are reported. The X-ray structures of two phthalonitriles and one ZnPc are presented. All hydroxy-substituted ZnPcs show low fluorescence quantum yields in DMSO and complete fluorescence quenching in aqueous solutions, but high singlet oxygen quantum yields in DMSO (0.2-0.7). Our results suggest that the tetra- and octa-hydroxy ZnPcs might find application as photosensitizers in the PDT treatment of cancer. © 2009 Elsevier Ltd. All rights reserved.
Publication Source (Journal or Book title)
Li, H., Nguyen, N., Fronczek, F., & Vicente, M. (2009). Syntheses and properties of octa-, tetra-, and di-hydroxy-substituted phthalocyanines. Tetrahedron, 65 (17), 3357-3363. https://doi.org/10.1016/j.tet.2009.02.012