Selectivity in molecularly imprinted matrices
© 2004 by Taylor & Francis Group, LLC. The experimentalist is often faced with the challenge of selectively separating a desired compound from a mixture and molecularly imprinted polymers (MIPs) can be instrumental in achieving such substrate selective separations. Polymers have been imprinted using organic molecules [1,2], metal ions [3-5], and large biomolecules such as proteins and DNA [6,7]. These different substrate types often require different strategies for optimal imprinting and recognition. However, most studies on molecular imprinting to date have focused on organic molecules, providing most of what is known about selectivity in MIPs.Therefore, treatment in this tutorial will correspondingly focus on imprinting small organic molecules. The category of organic molecule substrates can be further divided into: 1. enantiomeric organic molecules; 2. isomeric organic compounds; 3. different organic compounds.
Publication Source (Journal or Book title)
Molecularly Imprinted Materials: Science and Technology
Spivak, D. (2004). Selectivity in molecularly imprinted matrices. Molecularly Imprinted Materials: Science and Technology, 395-417. https://doi.org/10.1201/9781420030303