Molecular imprinting made easy
A simple method of molecular imprinting is presented that uses a single cross-linking monomer N,O-bismethacryloyl ethanolamine (NOBE) along with template, initiator, and solvent. This formulation eliminates the need for additional functional monomers and empirical optimization of relative ratios of functional monomers, cross-linkers, and template. In fact, utilization of NOBE alone often provides molecularly imprinted polymers (MIPs) with higher performance than MIPs incorporating functional monomer (e.g., methacrylic acid).
Publication Source (Journal or Book title)
Journal of the American Chemical Society
Sibrian-Vazquez, M., & Spivak, D. (2004). Molecular imprinting made easy. Journal of the American Chemical Society, 126 (25), 7827-7833. https://doi.org/10.1021/ja038961b