Porphyrin β-keto-esters and their cyclisation to phaeoporphyrins
Treatment of porphyrin carboximidazolides with the magnesium complex of methyl hydrogen malonate affords high yields of the corresponding β-keto-esters which are cyclised to phaeoporphyrins when treated with two equivalents of thallium trifluoroacetate followed by photolysis.
Publication Source (Journal or Book title)
Journal of the Chemical Society, Chemical Communications
Kenner, G., McCombie, S., & Smith, K. (1972). Porphyrin β-keto-esters and their cyclisation to phaeoporphyrins. Journal of the Chemical Society, Chemical Communications (14), 844-845. https://doi.org/10.1039/C39720000844