Pyrroles and related compounds. Part XXII. Syntheses of pyrro-methanes and a tripyrrane
Treatment of 2-acetoxymethylpyrroles with 2-unsubstituted pyrroles in either methanol or acetic acid containing a catalytic quantity (<0·1 equiv.) of toluene-p-sulphonic acid hydrate, affords high yields of the corresponding pyrromethanes. The reaction in methanol is modified to give an acceptable yield of the tripyrrane (15), a member of a class of compound of current biosynthetic interest.
Publication Source (Journal or Book title)
Journal of the Chemical Society, Perkin Transactions 1
Cavaleiro, J., Rocha Gonsalves, A., Kenner, G., & Smith, K. (1973). Pyrroles and related compounds. Part XXII. Syntheses of pyrro-methanes and a tripyrrane. Journal of the Chemical Society, Perkin Transactions 1, 2471-2478. https://doi.org/10.1039/p19730002471