Pyrroles and related compounds. Part XXIV. Separation and oxidative degradation of chlorophyll derivatives
A convenient, large-scale method for separation of the a and b series metal-free chlorophyll derivatives is described, utilising the Girard 'T' reagent with subsequent chromatography. Efficient procedures for conversion of phaeophytin-a (3) into rhodoporphyrin-XV dimethyl ester (1) and the corresponding 2-vinyl compound (2), involving the classical oxidation to purpurin derivatives, followed by further degradation, are described; n.m.r. data for several important chlorophyll degradation products are reported. Novel oxidative reactions of the isocyclic ring in methyl mesopyrophaeophorbide-a (19) are also described.
Publication Source (Journal or Book title)
Journal of the Chemical Society, Perkin Transactions 1
Kenner, G., McCombie, S., & Smith, K. (1973). Pyrroles and related compounds. Part XXIV. Separation and oxidative degradation of chlorophyll derivatives. Journal of the Chemical Society, Perkin Transactions 1, 2517-2523. https://doi.org/10.1039/p19730002517