On the partial synthesis of optically pure bacteriopheophorbides -C and -D
Methyl bacteriopheophorbides-c or -d (obtained by partial synthesis, or by Markownikoff hydration of methyl pyropheophorbide-a, respectively) are obtained as a mixture of the (R,S) diastereomers at the 2(1-hydroxyethyl) group; these can be efficiently and completely separated using reverse phase high performance liquid chromatography (HPLC). Purity of the resolved mixture is demonstrated by 360 MHz NMR spectra. © 1980.
Publication Source (Journal or Book title)
Smith, K., Bisset, G., & Tabba, H. (1980). On the partial synthesis of optically pure bacteriopheophorbides -C and -D. Tetrahedron Letters, 21 (12), 1101-1104. https://doi.org/10.1016/S0040-4039(01)83924-1