Title

Porphyrin Synthesis through Tripyrrins: An Alternate Approach

Document Type

Article

Publication Date

1-1-1983

Abstract

A new route for synthesis of unsymmetrically substituted porphyrins is described. The route follows the earlier approach through pyrromethanes, tripyrrin hydrobromides, and a,c-biladiene dihydrobromides, except that the pyrromethane intermediate is elongated in an initially “clockwise” direction to give a benzyl tripyrrincarboxylate. Various advantages over the tert-butyl tripyrrincarboxylates used in the earlier method (Scheme I) are discussed. The new route is demonstrated in the syntheses of five pure porphyrins required for other current studies. © 1983, American Chemical Society. All rights reserved.

Publication Source (Journal or Book title)

Journal of Organic Chemistry

First Page

4302

Last Page

4306

This document is currently not available here.

Share

COinS