Title

PHOTOSENSITIZATION WITH DERIVATIVES OF CHLOROPHYLL

Document Type

Article

Publication Date

1-1-1989

Abstract

Abstract The properties of several chlorophyll derivatives were examined: the methyl esters of pheophorbide A, pheophorbide B and pheophytin. In spite of structural differences, all products were equally effective sensitizers in vitro and were localized equally well by murine tumors in vivo after 1 h. But only the pheophytins persisted at neoplastic loci for 24 h. There was no evidence of hydrolysis of the methyl esters, but the phytyl ester linkage was labile in vivo. Copyright © 1989, Wiley Blackwell. All rights reserved

Publication Source (Journal or Book title)

Photochemistry and Photobiology

First Page

157

Last Page

160

This document is currently not available here.

Share

COinS