Title

Syntheses, stability, and tumorcidal activity of porphyrin dimers and trimers with ether linkages

Document Type

Article

Publication Date

1-1-1990

Abstract

The first syntheses of a series of regiochemically pure porphyrin dimers and trimers with ether linkages which are structurally related to Photofrin-II® are described. Stability of these oligomers was investigated using variable temperature proton NMR spectroscopy, and preliminary biological results reveal that manupulation of peripheral substituents causes a remarkable difference in photosensitizing ability in vivo. © 1990.

Publication Source (Journal or Book title)

Tetrahedron Letters

First Page

7399

Last Page

7402

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