Stepwise syntheses of unsymmetrical tetra-arylporphyrins. Adaptation of the macdonald dipyrrole self-condensation methodology
A new synthetic route to meso-tetraarylporphyrins [e.g. (12,13)] using a MacDonald-type 2+2 condensation is established. The method presented here shows wide applicability for the preparation of 5,10,15,20-tetra-arylsubstituted porphyrins with two-fold rotational symmetry. The 2+2 method is further extended to give a tetraarylporphyrin (14) bearing four different aryl groups in a predesignated array. © 1990.
Publication Source (Journal or Book title)
Wallace, D., & Smith, K. (1990). Stepwise syntheses of unsymmetrical tetra-arylporphyrins. Adaptation of the macdonald dipyrrole self-condensation methodology. Tetrahedron Letters, 31 (50), 7265-7268. https://doi.org/10.1016/S0040-4039(00)88540-8