Functionalizations of the alkyl substituents in octa-alkylporphyrins
Treatment of octaethylporphyrin (OEP; 1) with N-bromosuccinimide in the presence of 2,2′-azobis(2-methylpropionitrile) (AIBN) affords the trans-(2-bromovinyl)-heptaethylporphyrin 10 in high yield. When primary and secondary alcohols are present in the reaction mixture the corresponding (1-alkoxyethyl)-heptaethylporphyrins are formed. The trans-(2-bromovinyl)-heptaethylporphyrin undergoes some of the reactions characteristic of the vinyl groups in porphyrins and several reactions of this compound are described. © 1991.
Publication Source (Journal or Book title)
Vicente, M., & Smith, K. (1991). Functionalizations of the alkyl substituents in octa-alkylporphyrins. Tetrahedron, 47 (34), 6887-6894. https://doi.org/10.1016/S0040-4020(01)96144-7