Title

New Syntheses of benzoporphyrin derivatives and analogues for use in photodynamic therapy

Document Type

Article

Publication Date

1-1-1992

Abstract

An efficient route for the synthesis of isomerically pure benzoporphyrin derivative (BPD) is presented. To understand more about structure/activity relationships in photodynamic therapy, a series of BPD derivatives, including dimers linked with carbon-carbon bonds were also prepared. The structure of the most effective (ring A) BPD isomer (14) was confirmed by a single crystal X-ray study. © 1992.

Publication Source (Journal or Book title)

Bioorganic and Medicinal Chemistry Letters

First Page

1575

Last Page

1580

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