Title
New Syntheses of benzoporphyrin derivatives and analogues for use in photodynamic therapy
Document Type
Article
Publication Date
1-1-1992
Abstract
An efficient route for the synthesis of isomerically pure benzoporphyrin derivative (BPD) is presented. To understand more about structure/activity relationships in photodynamic therapy, a series of BPD derivatives, including dimers linked with carbon-carbon bonds were also prepared. The structure of the most effective (ring A) BPD isomer (14) was confirmed by a single crystal X-ray study. © 1992.
Publication Source (Journal or Book title)
Bioorganic and Medicinal Chemistry Letters
First Page
1575
Last Page
1580
Recommended Citation
Meunier, I., Pandey, R., Walker, M., Senge, M., Dougherty, T., & Smith, K. (1992). New Syntheses of benzoporphyrin derivatives and analogues for use in photodynamic therapy. Bioorganic and Medicinal Chemistry Letters, 2 (12), 1575-1580. https://doi.org/10.1016/S0960-894X(00)80433-3