Title

PHOTOSENSITIZATION WITH BACTERIOCHLORINS

Document Type

Article

Publication Date

1-1-1993

Abstract

Abstract— Biophysical and photobiological properties of a group of bacteriochlorins were compared with efficacy of these products for photodynamic therapy of murine tumors. Predictive factors for selective photosensitization in vivo include affinity binding to lipoproteins greater than albumin, extinction coefficient at the wavelength of irradiation and tumor/skin distribution. Efficacy was correlated with circulating plasma levels of the different sensitizers but not with the photodynamic therapy response in cell culture. Copyright © 1993, Wiley Blackwell. All rights reserved

Publication Source (Journal or Book title)

Photochemistry and Photobiology

First Page

200

Last Page

203

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