Title
Pharmaceutical analysis for environmental samples: Individual and simultaneous determination of ciprofloxacin, ofloxacin and norfloxacin using an HPLC with fluorescence and UV detection with a wetland soil matrix
Document Type
Article
Publication Date
11-26-2009
Abstract
Two HPLC methods were developed for individual and simultaneous determination of ciprofloxacin, norfloxacin and ofloxacin for use in laboratory experiments producing large numbers of samples (100 s to 1000 s). Individual compound detection produced retention times between 1.5 and 2 min and simultaneous detection between 6.5 to 8 min. The methods are compatible with complex geomatrices, e.g. a wetland soil. These methods provide 1) detection limits in the low parts per-billion range; 2) decrease in retention times of 5-10 times for single compounds, and up to 2 times for simultaneous detection over published methods; and 3) require no solid phase extraction. © Taylor & Francis Group, LLC.
Publication Source (Journal or Book title)
Analytical Letters
First Page
2937
Last Page
2950
Recommended Citation
Conkle, J., Lattao, C., White, J., & Cook, R. (2009). Pharmaceutical analysis for environmental samples: Individual and simultaneous determination of ciprofloxacin, ofloxacin and norfloxacin using an HPLC with fluorescence and UV detection with a wetland soil matrix. Analytical Letters, 42 (18), 2937-2950. https://doi.org/10.1080/00032710903201883