Syntheses of regiospecifically meso functionalized dipyrromethanes, porphyrins, and diphenylethane-linked bisporphyrins
Acid catalyzed condensation of 2-unsubstituted pyrroles with diethyl acetals permits preparation, in good yields, of a variety of meso-functionalized dipyrromethanes. Subsequent use in the so-called MacDonald "2 + 2" condensation provides 5-functionalized porphyrins and, eventually, benzochlorin derivatives. A novel application of a reductive coupling scheme, utilizing Ni(0), provides diphenylethane-linked bisporphyrins, which are potential models for electron transfer studies. © 1995.
Publication Source (Journal or Book title)
Lee, D., Brisson, J., & Smith, K. (1995). Syntheses of regiospecifically meso functionalized dipyrromethanes, porphyrins, and diphenylethane-linked bisporphyrins. Heterocycles, 40 (1), 131-135. https://doi.org/10.3987/com-94-s32