Title

Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy

Document Type

Article

Publication Date

5-12-1997

Abstract

Efficient syntheses and mechanisms of the formation of some novel porphyrins and chlorins with cyclic anhydride, imide and isoimide rings bearing various N-substituents as possible target-specific photosensitizers for photodynamic therapy are presented. Porphyrins with such cyclic ring systems are named as 'emeraldins' due to their intense green color. This class of compounds show a unique reverse etio-type absorption spectra.

Publication Source (Journal or Book title)

Tetrahedron Letters

First Page

3335

Last Page

3338

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