Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy
Efficient syntheses and mechanisms of the formation of some novel porphyrins and chlorins with cyclic anhydride, imide and isoimide rings bearing various N-substituents as possible target-specific photosensitizers for photodynamic therapy are presented. Porphyrins with such cyclic ring systems are named as 'emeraldins' due to their intense green color. This class of compounds show a unique reverse etio-type absorption spectra.
Publication Source (Journal or Book title)
Kozyrev, A., Zheng, G., Lazarou, E., Dougherty, T., Smith, K., & Pandey, R. (1997). Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy. Tetrahedron Letters, 38 (19), 3335-3338. https://doi.org/10.1016/S0040-4039(97)00621-7