Dynamics of liposomes in the fluid phase
© 2019 Elsevier Ltd We review the currently available material on the morphology and dynamics of phospholipids assembled into liposomes. Key information obtained from neutron scattering, nuclear magnetic resonance (NMR), and other techniques plays a crucial role in understanding the vital role of lipids in sustaining life in living organisms. We concentrate on the dynamics in the biologically important fluid phase in the time range from picoseconds to seconds, which includes a discussion of the center of mass diffusion of liposomes, membrane fluctuations; and lateral, rotational, and flip-flop motions of the lipids. We emphasize on the sensitivity of the dynamics on interactions with a variety of biologically relevant molecules such as cholesterol. By a comparison of data from literature, we witness a good agreement of the results from different techniques and studies.
Publication Source (Journal or Book title)
Current Opinion in Colloid and Interface Science
Gupta, S., De Mel, J., & Schneider, G. (2019). Dynamics of liposomes in the fluid phase. Current Opinion in Colloid and Interface Science, 42, 121-136. https://doi.org/10.1016/j.cocis.2019.05.003