Visible-light-promoted selenofunctionalization of alkenes
A visible-light-promoted method for the selenofunctionalization (and tellurofunctionalization) of alkenes has been developed. This method obviates the prepreparation of moisture-sensitive chalcogen electrophiles. The experimental setup is simple, and superior yields are obtained in the case of selenofunctionalization (up to 99%) while moderate to good yields are obtained in the case of tellurofunctionalization (53-75%). A variety of intra- and intermolecular processes and a short synthesis of the Amaryllidaceae alkaloid (±)-γ-lycorane are demonstrated with this method. © 2013 American Chemical Society.
Publication Source (Journal or Book title)
Conner, E., Crocker, K., Fernando, R., Fronczek, F., Stanley, G., & Ragains, J. (2013). Visible-light-promoted selenofunctionalization of alkenes. Organic Letters, 15 (21), 5558-5561. https://doi.org/10.1021/ol402753u