Title

On-line single droplet deposition for MALDI mass spectrometry

Document Type

Article

Publication Date

10-1-2004

Abstract

A single droplet generator was coupled with a rotating ball inlet matrix-assisted laser desorption/ionization (MALDI) time of flight (TOF) mass spectrometer. Single droplets with 100 picoliter volume were ejected by a piezoelectric-actuated droplet generator and deposited onto a matrix-coated rotating stainless steel ball at atmospheric pressure. The single droplet deposit was transported to the vacuum side of the instrument where ionization was accomplished using a UV pulsed laser. Using this on-line interface, it was possible to obtain protonated molecule signal from as little as 10 fmol analyte. © 2004 American Society for Mass Spectrometry.

Publication Source (Journal or Book title)

Journal of the American Society for Mass Spectrometry

First Page

1471

Last Page

1477

This document is currently not available here.

Share

COinS