"A Role for Exercise to Counter Skeletal Muscle Clock Disruption" by Melissa L. Erickson, Karyn A. Esser et al.

Faculty Publications

Title

A Role for Exercise to Counter Skeletal Muscle Clock Disruption

Authors

Melissa L. Erickson, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA.
Karyn A. Esser, Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL.
William E. Kraus, Duke Molecular Physiology Institute, Duke University, Durham, NC.
Thomas W. Buford
Leanne M. Redman, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA.

Document Type

Article

Publication Date

1-1-2021

Abstract

Disruption of the skeletal muscle circadian clock leads to a preferential shift toward lipid oxidation while reducing carbohydrate oxidation. These effects are apparent at the whole-body level, including glucose intolerance, increased energy expenditure, and fasting hyperglycemia. We hypothesize that exercise counters these metabolic disturbances by modifying the skeletal muscle clock and reverting substrate metabolism back toward an optimal substrate balance.

Publication Source (Journal or Book title)

Exercise and sport sciences reviews

First Page

Last Page

Recommended Citation

Erickson, M. L., Esser, K. A., Kraus, W. E., Buford, T. W., & Redman, L. M. (2021). A Role for Exercise to Counter Skeletal Muscle Clock Disruption. Exercise and sport sciences reviews, 49 (1), 35-41. https://doi.org/10.1249/JES.0000000000000235

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