Background: Substrate water must reach the buried Mn4O 5Ca cluster in Photosystem II. Results: OH produced by radiolysis modified buried amino acid residues. These were mapped onto the PS II crystal structure. Conclusion: Two groups of oxidized residues were identified which form putative pathways to the Mn4O5Ca cluster. Significance: Identification of water and oxygen channels is crucial for our understanding of Photosystem II function. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.
Publication Source (Journal or Book title)
Journal of Biological Chemistry
Frankel, L., Sallans, L., Bellamy, H., Goettert, J., Limbach, P., & Bricker, T. (2013). Radiolytic mapping of solvent-contact surfaces in photosystem II of higher plants: Experimental identification of putative water channels within the photosystem. Journal of Biological Chemistry, 288 (32), 23565-23572. https://doi.org/10.1074/jbc.M113.487033