Title

RIFL aims to be a new player in lipid metabolism

Document Type

Editorial

Publication Date

8-1-2012

Abstract

RIFL (refeeding induced in fat and liver) is highly expressed in brown and white fat as well as in liver. In white adipose tissue and liver, RIFL expression is induced by refeeding and is also elevated in ob/ob mice. The function of RIFL is unknown, and there is some evidence to suggest it may be secreted. RIFL expression is induced during adipogenesis in rodent and human model systems, and cellular knockdown and mouse knockout studies demonstrate that RIFL expression correlates with lipid levels. Overall, these studies indicate that RIFL is a new important player in lipid metabolism. © 2012 the American Physiological Society.

Publication Source (Journal or Book title)

American Journal of Physiology - Endocrinology and Metabolism

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