A consensus Alu repeat probe for physical mapping
Physical mappinf of the human genome involves a variety of complex hybridization-based procedures, some of which rely upon the ability to seperate human clones derived from human-rodent hybrid cell lines from those that contain background rodent-derived DNA sequences. The ability to block the repititive element (Alu repeat) portion of inter-Alu PCR products derived from a variety of complex sources is also crucial for the isolation of unique DNA sequences. Here we report the construction and characterization of a new consensus Alu repeat probe (pPD39) designed for these purposes. © 1994.
Publication Source (Journal or Book title)
Genetic Analysis: Biomolecular Engineering
Batzer, M., Alegria-Hartman, M., & Deininger, P. (1994). A consensus Alu repeat probe for physical mapping. Genetic Analysis: Biomolecular Engineering, 11 (2), 34-38. https://doi.org/10.1016/1050-3862(94)90058-2