Identification and analysis of a 'young' polymorphic Alu element
A polymorphic Alu element belonging to a young subfamily of Alu repeats has been identified. Sequence analysis showed that this Alu element is flanked by perfect direct repeats and a 3′ oligo(dA)-rich tail. The Alu element, designated A25, is deleted by 34 nucleotides at the 5′ end and has a single CpG mutation compared to the human-specific consensus sequence. Using a PCR-based assay, we demonstrated that the A25 Alu repeat is localized to human chromosome 8 and is polymorphic in humans. © 1995.
Publication Source (Journal or Book title)
BBA - Gene Structure and Expression
Arcot, S., Fontius, J., Deininger, P., & Batzer, M. (1995). Identification and analysis of a 'young' polymorphic Alu element. BBA - Gene Structure and Expression, 1263 (1), 99-102. https://doi.org/10.1016/0167-4781(95)00080-Z