Title

Identification and analysis of a 'young' polymorphic Alu element

Document Type

Article

Publication Date

7-25-1995

Abstract

A polymorphic Alu element belonging to a young subfamily of Alu repeats has been identified. Sequence analysis showed that this Alu element is flanked by perfect direct repeats and a 3′ oligo(dA)-rich tail. The Alu element, designated A25, is deleted by 34 nucleotides at the 5′ end and has a single CpG mutation compared to the human-specific consensus sequence. Using a PCR-based assay, we demonstrated that the A25 Alu repeat is localized to human chromosome 8 and is polymorphic in humans. © 1995.

Publication Source (Journal or Book title)

BBA - Gene Structure and Expression

First Page

99

Last Page

102

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