Title

Spectroscopic and structural study of flobufen

Document Type

Article

Publication Date

1-1-1995

Abstract

Flobufen, 4-(2′,4′-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoicacid, and its 3-methyl isomer have been obtained by the Friedel-Crafts reaction of 2,4-difluorobiphenyl with itaconic or citraconic anhydride, respectively, followed by hydrogenation of the products. The structures of both compounds have been elucidated by mass spectrometry and 1H, 13C and 19F NMR spectroscopy. The structure of flobufen has been confirmed by a single-crystal X-ray study. © 1995 Elsevier Science S.A. All rights reserved.

Publication Source (Journal or Book title)

Journal of Fluorine Chemistry

First Page

213

Last Page

219

This document is currently not available here.

Share

COinS