Title
Conformation of ergopeptam and ergopeptine alkaloids (ergocristam and ergocristine)
Document Type
Article
Publication Date
12-1-1997
Abstract
The crystal structures of two ergot alkaloids ergocristam (I) and ergocristine acetone solvate (II), have been determined by X-ray diffraction and compared with their conformation in solution obtained from NMR data. The presence of D-proline in I essentially influences the conformation of the alkaloid tripeptide moiety which seems likely to explain why I does not undergo further enzymatical hydroxylation and is found as a terminal step of ergot alkaloid biosynthesis.
Publication Source (Journal or Book title)
Zeitschrift fur Kristallographie
First Page
593
Last Page
600
Recommended Citation
Pakhomova, S., Ondráček, J., Hušák, M., Kratochvíl, B., Jegorov, A., Cvak, L., Sedmera, P., & Havlíček, V. (1997). Conformation of ergopeptam and ergopeptine alkaloids (ergocristam and ergocristine). Zeitschrift fur Kristallographie, 212 (8), 593-600. Retrieved from https://digitalcommons.lsu.edu/biosci_pubs/2863