Tetraalkylated 2,8,14,20-tetrathiacalixarenes: Novel infinite channels in the solid state
The synthesis of new tetraalkylated derivatives of 2,8,14,20- tetrahiacalixarenes was achieved by the refluxing of thiacalixarenes in acetone or acetonitrile with the alkylation agent (R-I, R-Br) in the presence of K2CO3 or Cs2CO3. The structure of the tetraalkylated thiacalixarenes was studied by means of H NMR experiments proving the 1,3- alternate conformation under measurement conditions (CDCl3, room temperature). The same conformation was established by X-ray analysis in the solid state where these derivatives create nice infinite channels.
Publication Source (Journal or Book title)
Lhoták, P., Himl, M., Pakhomova, S., & Stibor, I. (1998). Tetraalkylated 2,8,14,20-tetrathiacalixarenes: Novel infinite channels in the solid state. Tetrahedron Letters, 39 (48), 8915-8918. https://doi.org/10.1016/S0040-4039(98)01950-9