Social regulation of Gene Expression in the hypothalamic-pituitary-gonadal axis

Karen P. Maruska, Stanford University
Russell D. Fernald, Stanford University


Reproduction is a critically important event in every animals' life and in all vertebrates is controlled by the brain via the hypothalamic-pituitary-gonadal (HPG) axis. In many species, this axis, and hence reproductive fitness, can be profoundly influenced by the social environment. Here, we review how the reception of information in a social context causes genomic changes at each level of the HPG axis. ©2011 Int. Union Physiol. Sci./Am. Physiol. Soc.