Title

Occurrence of an unusual amount of an odd-numbered fatty acid in glycosphingolipids from human cataracts

Document Type

Article

Publication Date

1-1-1987

Abstract

Human cataractous glycosphingolipids were isolated and purified according to previously established procedures. Fatty acid analyses of the purified glycosphingolipid revealed the presence of a significant amount of an odd-chain fatty acid. This was confirmed by methane (CH4) chemical ionization mass spectrometry, which showed characteristic ions at m/z 397, 425, 437, and 365. These ions facilitated the determination of molecular weight and the assignment of C25.0 (n-penta-cosanoic acid) to this fatty acid in question. This may be the first time that such an unusual distribution of a single odd-chain fatty acid has been shown to occur in a glycosphingolipid from any tissue. © 1987 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

Publication Source (Journal or Book title)

Current Eye Research

First Page

1361

Last Page

1367

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