Hydrogenation selectivity of the Bicyclo[4.4.0]decane ring system of valencanes
To test the selectivity of sterically hindered systems, (+)-nootkatone and derivatives were subjected to a wide variety of hydrogenation methodologies. The steric impact of the C-4 methyl substituent seems to be responsible for the inability of the system to adopt the cis-fused structure. © Georg Thieme Verlag Stuttgart New York.
Publication Source (Journal or Book title)
Sauer, A., Crowe, W., Henderson, G., & Laine, R. (2010). Hydrogenation selectivity of the Bicyclo[4.4.0]decane ring system of valencanes. Synlett (3), 445-448. https://doi.org/10.1055/s-0029-1219206