As is the case with mammals in general, primate genomes are inundated with repetitive sequence. Although much of this repetitive content consists of "molecular fossils" inherited from early mammalian ancestors, a significant portion of this material comprises active mobile element lineages. Despite indications that these elements played a major role in shaping the architecture of the genome, there remain many unanswered questions surrounding the nature of the host-element relationship. Here we review advances in our understanding of the host-mobile element dynamic and its overall impact on primate evolution. © 2005 Wiley Periodicals, Inc.
Publication Source (Journal or Book title)
Hedges, D., & Batzer, M. (2005). From the margins of the genome: Mobile elements shape primate evolution. BioEssays, 27 (8), 785-794. https://doi.org/10.1002/bies.20268